Potassium thiocyanate → HCID 20387432, 화합물

HRID 1112225노트

반응식

HRID 1112225 반응식
Cl.Cl[CH2:3][CH2:4][S:5][CH2:6][C:7]1[N:8]=[CH:9][NH:10][C:11]=1[CH3:12].[S-:13][C:14]#[N:15].[K+]>C(O)C>[CH3:12][C:11]1[NH:10][CH:9]=[N:8][C:7]=1[CH2:6][S:5][CH2:4][CH2:3][S:13][C:14]#[N:15]

참가 물질

4

반응물 2

HCID 516872Potassium thiocyanateHCID 132173611-Chloro-2(5-methyl-4-imidazolylmethylthio)ethane hydrochloride

생성물 1

HCID 20387432HCID 20387432, 화합물

시약·촉매·용매 1

HCID 702Ethanol용매

실험 절차

1-Chloro-2-(5-methyl-4-imidazolylmethylthio)ethane hydrochloride (2.1 g) and potassium thiocyanate (0.97 g) were heated together under reflux in ethanol (50 ml) for 3 days. The mixture was evaporated to dryness and the residue was taken up in water, basified with sodium carbonate and extracted with chloroform. The chloroform extracts were dried (MgSO4) and evaporated to a residue which was recrystallised from acetonitrile to give 2-(5-methyl-4-imidazolylmethylthio)ethylthiocyanate m.p. 101°-103°.

후처리

  1. customThe mixture was evaporated to dryness
  2. extractionextracted with chloroform
  3. dry with materialThe chloroform extracts were dried (MgSO4)
  4. customevaporated to a residue which
  5. customwas recrystallised from acetonitrile

출처 및 근거

ORD 기록
ord-f5487bc3e1f94e9183d319abaa0876d8
출처 데이터셋
uspto-grants-1978_10
특허 번호
US04120972

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