Ethyl cyanoformate → Pirolate

HRID 1112241

반응식

HRID 1112241 반응식
[CH3:1][O:2][C:3]1[CH:4]=[C:5]2[C:10](=[CH:11][C:12]=1[O:13][CH3:14])[N:9]=[C:8]([NH2:15])[C:7]([C:16]([NH2:18])=[O:17])=[CH:6]2.[C:19]([C:21]([O:23][CH2:24][CH3:25])=[O:22])#N>C1C=CC=CC=1>[CH3:1][O:2][C:3]1[CH:4]=[C:5]2[C:10](=[CH:11][C:12]=1[O:13][CH3:14])[N:9]=[C:8]1[N:15]=[C:19]([C:21]([O:23][CH2:24][CH3:25])=[O:22])[NH:18][C:16](=[O:17])[C:7]1=[CH:6]2

참가 물질

4

반응물 2

HCID 69336Ethyl cyanoformateHCID 7815842-Amino-6,7-dimethoxyquinoline-3-carboxamide

생성물 1

HCID 135445830Pirolate

시약·촉매·용매 1

HCID 241Benzene용매

실험 절차

Still further, a mixture of 6,7-dimethoxy-2-aminoquinoline-3-carboxamide (0.5 g., 2 millimoles), ethyl cyanoformate (0.43 g., 44 millimiles) and benzene (30 ml.) is refluxed for three days. The mixture is then cooled, filtered and the solid extracted with chloroform. Concentration of the chloroform extract affords the product which is recrystallized from chloroform.

후처리

  1. temperatureis refluxed for three days
  2. temperatureThe mixture is then cooled
  3. filtrationfiltered
  4. extractionthe solid extracted with chloroform
  5. extractionConcentration of the chloroform extract
  6. customaffords the product which
  7. customis recrystallized from chloroform

출처 및 근거

ORD 기록
ord-dd5e7d5fefa5458a8f5c20ee8a84d550
출처 데이터셋
uspto-grants-1978_10
특허 번호
US04120962

연결된 노트

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