Tetrahydrofuran → 2-methyl-5-hydroxy-6-(N-(tert-butoxycarbonyl)piperidin-4-yloxy)-1-(4-cyanonaphth-1-yl)methylbenzimidazole

반응식

[CH2:47]([N+:48]([CH2:49][CH2:50][CH2:51][CH3:52])([CH2:53][CH2:54][CH2:55][CH3:56])[CH2:57][CH2:58][CH2:59][CH3:60])[CH2:61][CH2:62][CH3:63].[CH2:64]1[O:65][CH2:66][CH2:67][CH2:68]1.[CH3:1][c:2]1[n:3][c:4]2[c:5]([n:6]1[CH2:7][c:8]1[cH:9][cH:10][c:11]([C:18]#[N:19])[c:12]3[cH:13][cH:14][cH:15][cH:16][c:17]13)[cH:20][c:21]([O:32][CH:33]1[CH2:34][CH2:35][N:36]([C:39](=[O:40])[O:41][C:42]([CH3:43])([CH3:44])[CH3:45])[CH2:37][CH2:38]1)[c:22]([O:24][Si:25]([C:26]([CH3:27])([CH3:28])[CH3:29])([CH3:30])[CH3:31])[cH:23]2.[F-:46]>>[CH3:1][c:2]1[n:3][c:4]2[c:5]([n:6]1[CH2:7][c:8]1[cH:9][cH:10][c:11]([C:18]#[N:19])[c:12]3[cH:13][cH:14][cH:15][cH:16][c:17]13)[cH:20][c:21]([O:32][CH:33]1[CH2:34][CH2:35][N:36]([C:39](=[O:40])[O:41][C:42]([CH3:43])([CH3:44])[CH3:45])[CH2:37][CH2:38]1)[c:22]([OH:24])[cH:23]2