Dichloromethane → 6-(3-(2,4-Difluorophenyl)-1-(1-(methylsulfonyl)pyrrolidin-3-yl)-1H-pyrazol-4-yl)-3-isopropyl-[1,2,4]triazolo[4,3-b]pyridazine

반응식

[CH3:40][S:41]([Cl:42])(=[O:43])=[O:44].[CH:31]([N:32]([CH2:33][CH3:34])[CH:35]([CH3:36])[CH3:37])([CH3:38])[CH3:39].[Cl:45][CH2:46][Cl:47].[F:1][c:2]1[c:3](-[c:9]2[n:10][n:11]([CH:26]3[CH2:27][NH:28][CH2:29][CH2:30]3)[cH:12][c:13]2-[c:14]2[cH:15][cH:16][c:17]3[n:18]([n:19]2)[c:20]([CH:23]([CH3:24])[CH3:25])[n:21][n:22]3)[cH:4][cH:5][c:6]([F:8])[cH:7]1>>[F:1][c:2]1[c:3](-[c:9]2[n:10][n:11]([CH:26]3[CH2:27][N:28]([S:41]([CH3:40])(=[O:43])=[O:44])[CH2:29][CH2:30]3)[cH:12][c:13]2-[c:14]2[cH:15][cH:16][c:17]3[n:18]([n:19]2)[c:20]([CH:23]([CH3:24])[CH3:25])[n:21][n:22]3)[cH:4][cH:5][c:6]([F:8])[cH:7]1