Phosphorus oxychloride → (+/-)-3-benzyl-7-chloro-2-{1-[2-(3-fluoro-4-methyl-phenyl)-4,4-dimethyl-4,5-dihydro-imidazol-1-yl]-2-methyl-propyl}-3H-quinazolin-4-one

반응식

[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[n:8]1[c:9]([CH:20]([CH:21]([CH3:22])[CH3:23])[NH:24][CH2:25][C:26]([CH3:27])([CH3:28])[NH:29][C:30]([c:31]2[cH:32][c:33]([F:38])[c:34]([CH3:37])[cH:35][cH:36]2)=[O:39])[n:10][c:11]2[cH:12][c:13]([Cl:19])[cH:14][cH:15][c:16]2[c:17]1=[O:18].[P:40]([Cl:41])([Cl:42])([Cl:43])=[O:44]>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[n:8]1[c:9]([CH:20]([CH:21]([CH3:22])[CH3:23])[N:24]2[CH2:25][C:26]([CH3:27])([CH3:28])[N:29]=[C:30]2[c:31]2[cH:32][c:33]([F:38])[c:34]([CH3:37])[cH:35][cH:36]2)[n:10][c:11]2[cH:12][c:13]([Cl:19])[cH:14][cH:15][c:16]2[c:17]1=[O:18]