Diisopropylethylamine → tert-Butyl 4-(5-bromo-3-methylpyridin-2-yl)piperazine-1-carboxylate

반응식

[Br:1][c:2]1[n:3][cH:4][c:5]([Br:9])[cH:6][c:7]1[CH3:8].[C:10]([CH3:11])([CH3:12])([CH3:13])[O:14][C:15](=[O:16])[N:17]1[CH2:18][CH2:19][NH:20][CH2:21][CH2:22]1.[CH:23]([N:24]([CH2:25][CH3:26])[CH:27]([CH3:28])[CH3:29])([CH3:30])[CH3:31]>>[c:2]1([N:20]2[CH2:19][CH2:18][N:17]([C:15]([O:14][C:10]([CH3:11])([CH3:12])[CH3:13])=[O:16])[CH2:22][CH2:21]2)[n:3][cH:4][c:5]([Br:9])[cH:6][c:7]1[CH3:8]

참가 물질

반응물 3

HCID 81531Diisopropylethylamine

HCID 143452tert-Butyl piperazine-1-carboxylate

HCID 8176802,5-Dibromo-3-methylpyridine

생성물 1

HCID 46739269tert-Butyl 4-(5-bromo-3-methylpyridin-2-yl)piperazine-1-carboxylate

출처 및 근거

ORD 기록: ord-02d34c78b7924bf195979835cc11cffd
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (7/10)
DOI: 10.1039/C8SC04228D

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