Tetrahydrofuran → 1-(3-(6-Ethoxy-7-methoxyquinazolin-4-ylthio)phenyl)-3-(5-(1,1,1-trifluoro-2-methylpropan-2-yl)isoxazol-3-yl)urea

반응식

[CH2:1]([CH3:2])[O:3][c:4]1[cH:5][c:6]2[c:7]([S:16][c:17]3[cH:18][c:19]([NH2:20])[cH:21][cH:22][cH:23]3)[n:8][cH:9][n:10][c:11]2[cH:12][c:13]1[O:14][CH3:15].[CH2:46]1[O:47][CH2:48][CH2:49][CH2:50]1.[CH3:51][N:52]([CH3:53])[c:54]1[cH:55][cH:56][n:57][cH:58][cH:59]1.[F:24][C:25]([C:26]([CH3:27])([CH3:28])[c:29]1[cH:30][c:31]([NH:34][C:35]([O:36][c:38]2[cH:39][cH:40][cH:41][cH:42][cH:43]2)=[O:37])[n:32][o:33]1)([F:44])[F:45]>>[CH2:1]([CH3:2])[O:3][c:4]1[cH:5][c:6]2[c:7]([S:16][c:17]3[cH:18][c:19]([NH:20][C:35]([NH:34][c:31]4[cH:30][c:29]([C:26]([C:25]([F:24])([F:44])[F:45])([CH3:27])[CH3:28])[o:33][n:32]4)=[O:36])[cH:21][cH:22][cH:23]3)[n:8][cH:9][n:10][c:11]2[cH:12][c:13]1[O:14][CH3:15]