Hydrochloric Acid → N-(3',4'-dimethoxycinnamoyl)anthranilic acid

HRID 1153882노트

반응식

HRID 1153882 반응식
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH:20]=[CH:21][C:22]=1[O:23][CH3:24])[CH:6]=[CH:7][C:8]([NH:10][C:11]1[C:12](=[CH:16][CH:17]=[CH:18][CH:19]=1)[C:13]([O-:15])=[O:14])=[O:9].[NH2+]1CCOCC1.Cl>O>[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH:20]=[CH:21][C:22]=1[O:23][CH3:24])[CH:6]=[CH:7][C:8]([NH:10][C:11]1[C:12](=[CH:16][CH:17]=[CH:18][CH:19]=1)[C:13]([OH:15])=[O:14])=[O:9]

참가 물질

4

반응물 2

HCID 313Hydrochloric AcidHCID 70467859HCID 70467859, 화합물

생성물 1

HCID 5527N-(3',4'-dimethoxycinnamoyl)anthranilic acid수율 98%

시약·촉매·용매 1

HCID 962Water용매

실험 절차

A 20 g quantity of morpholinium N-(3,4-dimethoxycinnamoyl)anthranilate is dissolved in 40 ml of water and the resultant solution is added dropwise to 45 ml of diluted hydrochloric acid (5 ml of conc. hydrochloric acid and 40 ml of water) with stirring. The precipitated crystals which form are collected by filtration, washed with water and then dried at 90°-100° C. under reduced pressure for 3 hours to yield 15.5 g of N-(3,4-dimethoxycinnamoyl)anthranilic acid (98% yield). The compound is confirmed as identical to that obtained in EXAMPLE VI.

후처리

  1. filtrationThe precipitated crystals which form are collected by filtration
  2. washwashed with water
  3. customdried at 90°-100° C. under reduced pressure for 3 hours

출처 및 근거

ORD 기록
ord-859d77f5e83a481592deb5243f6c1756
출처 데이터셋
uspto-grants-1984_12
특허 번호
US04486597

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