Acetic Acid → 4-Chloro-1-naphthol

HRID 1154764

반응식

HRID 1154764 반응식
[Cl:1][C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[C:5]([O:12]C)=[CH:4][CH:3]=1.C(O)(=O)C.Br>O>[Cl:1][C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[C:5]([OH:12])=[CH:4][CH:3]=1

참가 물질

5

반응물 3

HCID 176Acetic AcidHCID 260Hydrogen BromideHCID 6060381-Chloro-4-methoxynaphthalene

생성물 1

HCID 117874-Chloro-1-naphthol

시약·촉매·용매 1

HCID 962Water용매

실험 절차

The known compound 1-chloro-4-methoxynaphthalene is dissolved in 150 ml. of acetic acid and 150 ml. of 48 percent hydrobromic acid, and the mixture is heated at its reflux temperature for two hours. The mixture is diluted with 200 ml. of water and cooled to provide 1-chloro-4-hydroxynaphthalene as a crystalline solid.

후처리

  1. temperaturereflux temperature for two hours
  2. additionThe mixture is diluted with 200 ml

출처 및 근거

ORD 기록
ord-cf98ec7481b9439296a23a163b3da4a2
출처 데이터셋
uspto-grants-1981_11
특허 번호
US04298532

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