Tiopronin → HCID 56608455, 화합물

HRID 1155144

반응식

HRID 1155144 반응식
[SH:1][CH:2]([CH3:10])[C:3]([NH:5][CH2:6][C:7]([OH:9])=[O:8])=[O:4].[C:11]1([C:17]([C:25]2[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=2)([C:19]2[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=2)O)[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1>FC(F)(F)C(O)=O>[C:17]([S:1][CH:2]([CH3:10])[C:3]([NH:5][CH2:6][C:7]([OH:9])=[O:8])=[O:4])([C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1)([C:25]1[CH:26]=[CH:27][CH:28]=[CH:29][CH:30]=1)[C:19]1[CH:20]=[CH:21][CH:22]=[CH:23][CH:24]=1

참가 물질

4

반응물 2

HCID 5483TioproninHCID 6457Triphenylcarbinol

생성물 1

HCID 56608455HCID 56608455, 화합물

시약·촉매·용매 1

HCID 6422Trifluoroacetic acid용매

실험 절차

To a solution of alpha-mercaptopropionyl glycine (50 g; 0.307 moles) in 300 ml of trifluoroacetic acid, were added 79.9 g (0.307 moles) of triphenylcarbinol. The thus obtained solution was kept under stirring at room temperature for 15 minutes. The excess of trifluoroacetic acid was removed by evaporation and the residue taken up with ether. Filtration yielded a white solid, which was then washed with ether and dried in vacuo to constant weight.

후처리

  1. customThe excess of trifluoroacetic acid was removed by evaporation
  2. filtrationFiltration
  3. customyielded a white solid, which
  4. washwas then washed with ether
  5. customdried in vacuo to constant weight

출처 및 근거

ORD 기록
ord-c35d75ee4e0a4b42801e8a21fcc5aea0
출처 데이터셋
uspto-grants-1981_11
특허 번호
US04299842

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