Dodecanedial → Cyclopentadeca-2,14-dien-1-one

HRID 1155589노트

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HRID 1155589 반응식
COP([CH2:7][C:8](=O)[CH:9]=[CH:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH:21]=[O:22])(OC)=O.C(=O)CCCCCCCCCCC=O.COP(CC(=O)CP(OC)(OC)=O)(OC)=O>C(O)(C)(C)C>[C:21]1(=[O:22])[CH:20]=[CH:19][CH2:18][CH2:17][CH2:16][CH2:15][CH2:14][CH2:13][CH2:12][CH2:11][CH2:10][CH2:9][CH:8]=[CH:7]1

참가 물질

5

반응물 3

HCID 5743459DodecanedialHCID 13512255HCID 13512255, 화합물HCID 5421448415-(Dimethylphosphono)-pentadec-12-en-14-on-1-al

생성물 1

HCID 53676690Cyclopentadeca-2,14-dien-1-one수율 26%

시약·촉매·용매 1

HCID 6386tert-Butanol용매

실험 절차

The above reaction was repeated, but 15-(dimethylphosphono)-pentadec-12-en-14-on-1-al was replaced by a mixture of 0.79 g (4 mMole) of dodecan-1,12-dial and 1.10 g (4 mMole) of 1,3-bis(dimethylphosphono)-propan-2-one in 10 ml of 90% t-butanol. Identical introduction time and work up gave 229 mg (26%) of cyclopentadeca-2,14-dien-1-one in a similar ratio of isomers

후처리

  1. customThe above reaction

출처 및 근거

ORD 기록
ord-4cca4c4ed9ce49e5bb3fb4f1673397d5
출처 데이터셋
uspto-grants-1981_11
특허 번호
US04302607

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