HCID 20535629, 화합물 → CHROMONE2CARBOXYLICACID52HYDROXYPROPOXY8PROPYL

HRID 1156225노트

반응식

HRID 1156225 반응식
O1CCCCC1[O:7][CH:8]([CH3:28])[CH2:9][O:10][C:11]1[C:16]2[C:17](=[O:24])[CH:18]=[C:19]([C:21]([OH:23])=[O:22])[O:20][C:15]=2[C:14]([CH2:25][CH2:26][CH3:27])=[CH:13][CH:12]=1>C(O)C.O.Cl>[OH:7][CH:8]([CH3:28])[CH2:9][O:10][C:11]1[C:16]2[C:17](=[O:24])[CH:18]=[C:19]([C:21]([OH:23])=[O:22])[O:20][C:15]=2[C:14]([CH2:25][CH2:26][CH3:27])=[CH:13][CH:12]=1

참가 물질

5

반응물 1

HCID 20535629HCID 20535629, 화합물

생성물 1

HCID 121899CHROMONE2CARBOXYLICACID52HYDROXYPROPOXY8PROPYL

시약·촉매·용매 3

HCID 313Hydrochloric Acid촉매HCID 702Ethanol용매HCID 962Water용매

실험 절차

A suspension of 5-[2-(tetrahydropyran-2-yloxy)propoxy]-4-oxo-8-propyl-4H-1-benzopyran-2-carboxylic acid (0.12 g) in ethanol (3 ml), water (2 ml) and concentrated hydrochloric acid (1 drop) was stirred for 15 minutes at ambient temperature. The mixture was then extracted with chloroform (3×20 ml) and the chloroform extracts bulked, dried and evaporated in vacuo. The residue was crystallised from acetone giving 5-(2-hydroxypropoxy)-4-oxo-8-propyl-4H-1-benzopyran-2-carboxylic acid m.g. 134°-135° C.

후처리

  1. extractionThe mixture was then extracted with chloroform (3×20 ml)
  2. customdried
  3. customevaporated in vacuo
  4. customThe residue was crystallised from acetone

출처 및 근거

ORD 기록
ord-b0ea262d5a494c7eae27cdfd0e2e25cd
출처 데이터셋
uspto-grants-1982_06
특허 번호
US04335048

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