2,3-Dichloro-4-methoxycinnamic acid → 3-(2,3-Dichloro-4-methoxyphenyl)-propanoic acid

HRID 1157040노트

반응식

HRID 1157040 반응식
[Cl:1][C:2]1[C:12]([Cl:13])=[C:11]([O:14][CH3:15])[CH:10]=[CH:9][C:3]=1[CH:4]=[CH:5][C:6]([OH:8])=[O:7]>O1CCCC1.[Pt]>[Cl:1][C:2]1[C:12]([Cl:13])=[C:11]([O:14][CH3:15])[CH:10]=[CH:9][C:3]=1[CH2:4][CH2:5][C:6]([OH:8])=[O:7]

참가 물질

4

반응물 1

HCID 536752552,3-Dichloro-4-methoxycinnamic acid

생성물 1

HCID 128069603-(2,3-Dichloro-4-methoxyphenyl)-propanoic acid

시약·촉매·용매 2

HCID 23939Platinum촉매HCID 8028Tetrahydrofuran용매

실험 절차

2,3-Dichloro-4-methoxycinnamic acid (200.8 g., 0.813 mole) is dissolved in tetrahydrofuran (1600 ml.) and 5% platinum on charcoal (16.3 gm.) is added. The mixture is divided into 8 separate units and each is placed in a Parr hydrogenation apparatus in an atmosphere of hydrogen at an initial pressure of 50 p.s.i. Upon shaking, the time required for the reduction of each batch is 35 to 60 minutes.

후처리

  1. customseparate units

출처 및 근거

ORD 기록
ord-73b05e8912c34fedb299d922f926aea6
출처 데이터셋
uspto-grants-1982_06
특허 번호
US04337354

반응 노트

불러오는 중…