Hydrochloric Acid → HCID 68423386, 화합물

HRID 1157180

반응식

HRID 1157180 반응식
C(OC([N:8]1[CH2:13][CH2:12][CH:11]([NH:14][C:15]2[CH:20]=[CH:19][C:18]([C:21]3[N:26]=[CH:25][CH:24]=[CH:23][N:22]=3)=[CH:17][CH:16]=2)[CH2:10][CH2:9]1)=O)(C)(C)C.[ClH:27]>>[ClH:27].[NH:8]1[CH2:9][CH2:10][CH:11]([NH:14][C:15]2[CH:16]=[CH:17][C:18]([C:21]3[N:22]=[CH:23][CH:24]=[CH:25][N:26]=3)=[CH:19][CH:20]=2)[CH2:12][CH2:13]1

참가 물질

3

반응물 2

HCID 313Hydrochloric AcidHCID 589851534-(4-Pyrimidin-2-yl-phenylamino)-piperidine-1-carboxylic acid tert-butyl ester

생성물 1

HCID 68423386HCID 68423386, 화합물

실험 절차

Stirred 4-(4-Pyrimidin-2-yl-phenylamino)-piperidine-1-carboxylic acid tert-butyl ester (110 mg, 0.310 mmol) in 4M HCl (20 ml) at room temperature for 1 hour. Solvent was evaporated yielding desired product piperidin-4-yl-(4-pyrimidin-2-yl-phenyl)-amine, hydrochloride (114 mg).

후처리

  1. customSolvent was evaporated

출처 및 근거

ORD 기록
ord-a069523144e74a46bc0076cc7a5df77f
출처 데이터셋
uspto-grants-2010_10
특허 번호
US07807672B2

연결된 노트

불러오는 중…