1,1'-Biphenyl, 3-nitro- → 3-Aminobiphenyl

HRID 1158191

반응식

HRID 1158191 반응식
[N+:1]([C:4]1[CH:5]=[C:6]([C:10]2[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=2)[CH:7]=[CH:8][CH:9]=1)([O-])=O>[Pd].CO>[NH2:1][C:4]1[CH:5]=[C:6]([C:10]2[CH:11]=[CH:12][CH:13]=[CH:14][CH:15]=2)[CH:7]=[CH:8][CH:9]=1

참가 물질

4

반응물 1

HCID 164501,1'-Biphenyl, 3-nitro-

생성물 1

HCID 167173-Aminobiphenyl수율 77.1%

시약·촉매·용매 2

HCID 23938Palladium촉매HCID 887Methanol용매

실험 절차

3-nitrobiphenyl (500 mg, 2.5 mmol) and 10% palladium on carbon (267 mg, 2.5 mmol) were dissolved in methanol (1 mL) and purged with nitrogen and placed under an atmosphere of hydrogen overnight. The reaction mixture was filtered and evaporated to yield 326 mg of the desired amine, which was used directly in Example 12.

후처리

  1. custompurged with nitrogen
  2. filtrationThe reaction mixture was filtered
  3. customevaporated

출처 및 근거

ORD 기록
ord-fb8eac53c5df4318868e93e72310194f
출처 데이터셋
uspto-grants-2010_10
특허 번호
US07807713B2

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