Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Acetonitrile → Phenyl-cyclopropyl-carbamoyl chloride
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Acetonitrile | HCID 6342 | — |
| 반응물 | N-Cyclopropylaniline | HCID 7016287 | — |
| 반응물 | N-benzyl-N-methylcarbamoyl chloride | HCID 10464985 | — |
| 반응물 | Acetonitrile--water (1/1) | HCID 18373917 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | Phenyl-cyclopropyl-carbamoyl chloride | HCID 86622398 | — |
반응 단계
The title compound is prepared analogously as described for benzyl-methyl-carbamoyl chloride from cyclopropyl-phenyl-amine prepared according to 0 Synlett 2003, 14, 2139. MS (LC-MS): [M+H]+=196.2. tR (HPLC, Waters Symmetry C18 column, 20-95% CH3CN/H2O/3.5 min, 95% CH3CN/H2O, 2 min, CH3CN and H2O containing 0.1% TFA, flow: 0.6 mL/min): 4.44 min.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07807709B2 |
| 출처 데이터셋 | uspto-grants-2010_10 |
| ORD ID | ord-7d732f21f81c47b18d4e7f8f79e41c59 |
| 출처 메모 | uspto-grants-2010_10 |