Bromomethylcyclopropane → Indole

HRID 1159147노트

반응식

HRID 1159147 반응식
F[C:2]1[CH:10]=[C:9]2[C:5]([CH:6]=[CH:7][NH:8]2)=[CH:4][CH:3]=1.C1(CBr)CC1.N1C=CC=CC=1SC1SC(N)=NC=1>>[NH:8]1[C:9]2[C:5](=[CH:4][CH:3]=[CH:2][CH:10]=2)[CH:6]=[CH:7]1

참가 물질

4

반응물 3

HCID 81503BromomethylcyclopropaneHCID 3512786-FluoroindoleHCID 157291575-(Pyridin-2-ylsulfanyl)-thiazol-2-ylamine

생성물 1

HCID 798Indole

실험 절차

6-fluoroindole, R5X=cyclopropyl-methylbromide; NH2A=5-(pyridin-2-ylsulfanyl)-thiazole-2-ylamine

출처 및 근거

ORD 기록
ord-5563f6bea4cd43b79f848bad42ba2dfc
출처 데이터셋
uspto-grants-2010_10
특허 번호
US07812043B2

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