Propylene Glycol → 1,1,1,3,3,3-Hexafluoro-2-propanol

HRID 1160441

반응식

C(O)C(O)C.C1(C)CCC(C(C)C)C(O)C1.C(F)[O:18][CH:19]([C:24]([F:27])([F:26])[F:25])[C:20]([F:23])([F:22])[F:21]>>[CH:19]([OH:18])([C:24]([F:27])([F:26])[F:25])[C:20]([F:23])([F:22])[F:21]

참가 물질

반응물 3

HCID 1030Propylene Glycol

HCID 1254Menthol

HCID 5206Sevoflurane

생성물 1

HCID 135291,1,1,3,3,3-Hexafluoro-2-propanol

실험 절차

Table 2 resumes the tests realized with the agents propylene glycol and menthol proposed for the stabilization of sevoflurane against the degradation by alumina and the results for total impurity and for the single impurity HFIP obtained with and without alumina after stress at 60° C. for 22 hours. The total impurity is the sum of the ratio between the area for each impurity and the area of the internal standard (toluene) and HFIP is the ratio between the area of HFIP and the area of toluene obtained in the chromatograms.

출처 및 근거

ORD 기록: ord-177e0a2589fe43c586745e7dff6de1e8
출처 데이터셋: uspto-grants-2010_10
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07816409B2

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