Hydroxyamine hydrochloride → HCID 178492604, 화합물
반응식
C([O-])(=O)C.[Na+].[CH3:6][O:7][C:8]1[CH:17]=[CH:16][C:11]([O:12][CH2:13][C:14]#[N:15])=[CH:10][CH:9]=1.Cl.[NH2:19][OH:20]>CO>[OH:20][NH:19][C:14](=[NH:15])[CH2:13][O:12][C:11]1[CH:16]=[CH:17][C:8]([O:7][CH3:6])=[CH:9][CH:10]=1참가 물질
5
실험 절차
Add sodium acetate (5.1 g, 62 mmol) to 4-methoxyphenoxyacetonitrile (5.0 g, 31 mmol) and hydroxylamine hydrochloride (4.3 g, 62 mmol) in methanol (100 mL). Stir the resulting mixture at room temperature for 20 hours. Filter the resulting mixture through Celite, concentrate, stir in chloroform for 18 hours and filter. Concentrate the resulting solution to the title compound (5.1 g). LC-MS (m/e): 197 (M+1).
후처리
- filtrationFilter the resulting mixture through Celite
- concentrationconcentrate
- stirringstir in chloroform for 18 hours
- filtrationfilter
- concentrationConcentrate the resulting solution to the title compound (5.1 g)
출처 및 근거
- ORD 기록
- ord-1af38f65867c4301905b1cbbcd1d3c24
- 출처 데이터셋
- uspto-grants-2010_10
- 특허 번호
- US07816523B2
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