Hydrochloric Acid → {[4-(4-Isopropyl-phenyl)-thiazol-2-yl]-thiophen-2-ylmethyl-sulfamoyl}-acetic acid
반응식
C([O:5][C:6](=[O:32])[CH2:7][S:8](=[O:31])(=[O:30])[N:9]([C:16]1[S:17][CH:18]=[C:19]([C:21]2[CH:26]=[CH:25][C:24]([CH:27]([CH3:29])[CH3:28])=[CH:23][CH:22]=2)[N:20]=1)[CH2:10][C:11]1[S:12][CH:13]=[CH:14][CH:15]=1)(C)(C)C.Cl>>[CH:27]([C:24]1[CH:23]=[CH:22][C:21]([C:19]2[N:20]=[C:16]([N:9]([CH2:10][C:11]3[S:12][CH:13]=[CH:14][CH:15]=3)[S:8]([CH2:7][C:6]([OH:32])=[O:5])(=[O:30])=[O:31])[S:17][CH:18]=2)=[CH:26][CH:25]=1)([CH3:29])[CH3:28]참가 물질
3
실험 절차
The above ester was treated with 4M HCl as outlined in general procedure G1 to provide {[4-(4-Isopropyl-phenyl)-thiazol-2-yl]-thiophen-2-ylmethyl-sulfamoyl}-acetic acid. LCMS m/z: 438 (M+1)+.
출처 및 근거
- ORD 기록
- ord-8e8ebdbd7a044317bc611066d2c81548
- 출처 데이터셋
- uspto-grants-2010_10
- 특허 번호
- US07820704B2
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