Acetic Anhydride → 3-Methyl-7-(o-tolylthio)-2,3-dihydrobenzofuran-2-one
반응식
O[C:2]1[C:7]([S:8][C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][C:10]=2[CH3:15])=[CH:6][CH:5]=[CH:4][C:3]=1[CH:16]([CH3:20])[C:17]([OH:19])=[O:18].C(OC(=O)C)(=O)C>>[CH3:20][CH:16]1[C:3]2[CH:4]=[CH:5][CH:6]=[C:7]([S:8][C:9]3[CH:14]=[CH:13][CH:12]=[CH:11][C:10]=3[CH3:15])[C:2]=2[O:18][C:17]1=[O:19]참가 물질
3
실험 절차
A mixture of 2-[2-hydroxy-3-(o-tolylthio)phenyl]propionic acid (2.0 g) and acetic anhydride (5 ml) was refluxed under heating and evaporated under reduced pressure. The residue was purified by column chromatography (silica gel 30 g, benzene) to give 3-methyl-7-(o-tolylthio)-2,3-dihydrobenzofuran-2-one (1.4 g).
후처리
- temperaturewas refluxed
- temperatureunder heating
- customevaporated under reduced pressure
- customThe residue was purified by column chromatography (silica gel 30 g, benzene)
출처 및 근거
- ORD 기록
- ord-5fba9a8a67a54bcf9783b8989b6d6d1a
- 출처 데이터셋
- uspto-grants-1983_01
- 특허 번호
- US04367238
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