Hydrazine hydrate (1:1) → 2,3-Dichloro-4-trifluoromethyl-phenylhydrazine
반응식
[Cl:1][C:2]1[C:7]([Cl:8])=[C:6](Cl)[CH:5]=[CH:4][C:3]=1[C:10]([F:13])([F:12])[F:11].O.[NH2:15][NH2:16]>N1C=CC=CC=1>[Cl:8][C:7]1[C:2]([Cl:1])=[C:3]([C:10]([F:13])([F:12])[F:11])[CH:4]=[CH:5][C:6]=1[NH:15][NH2:16]참가 물질
4
실험 절차
100 g of 2,3,4-trichlorobenzotrifluoride are initially introduced, 200 ml of pyridine are added, followed by 100 g of hydrazine hydrate and the mixture is then heated to the reflux temperature for 12 hours. Thereafter, 90% of the pyridine is distilled off and the remaining residue is stirred into 250 ml of water. The crystalline product is filtered off under suction, washed with a little water and dried. 78 g of 2,3-dichloro-4-trifluoromethyl-phenylhydrazine having a melting point of 79° to 80° C. are obtained.
후처리
- temperaturethe mixture is then heated to the reflux temperature for 12 hours
- distillationThereafter, 90% of the pyridine is distilled off
- filtrationThe crystalline product is filtered off under suction
- washwashed with a little water
- customdried
출처 및 근거
- ORD 기록
- ord-4811186d4db94749a7fded0ce88227b6
- 출처 데이터셋
- uspto-grants-1990_03
- 특허 번호
- US04909832
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