Chlorosulfonic acid → HCID 22998500, 화합물
반응식
[CH2:1]([C:8]1[S:9][CH:10]=[CH:11][CH:12]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.Cl[S:14]([OH:17])(=[O:16])=[O:15]>C(Cl)(Cl)Cl>[CH2:1]([C:8]1[S:9][C:10]([S:14]([OH:17])(=[O:16])=[O:15])=[CH:11][CH:12]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1참가 물질
4
반응 조건
- 온도
- 0 °C
실험 절차
To a solution of 2-benzylthiophene (0.875 g, 5 mmol) in chloroform (2 ml) at 0° C. was added chlorosulfonic acid dropwise and the reaction was stirred at 0° C. for 30 min. The reaction mixture was decomposed by pouring onto crushed ice (20 g). The mixture was extracted with ethyl acetate, dried over MgSO4 and filtered. The solvent was removed under reduced pressure to give 5-benzylthiophene-2-sulfonic acid.
후처리
- additionby pouring
- extractionThe mixture was extracted with ethyl acetate
- dry with materialdried over MgSO4
- filtrationfiltered
- customThe solvent was removed under reduced pressure
출처 및 근거
- ORD 기록
- ord-6076998e9fb743608d0aadbf2a691d3d
- 출처 데이터셋
- uspto-grants-2003_09
- 특허 번호
- US06613804B2
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