1-Bromo-3-chloropropane → HCID 22994370, 화합물

HRID 1167859노트

반응식

HRID 1167859 반응식
[F:1][C:2]1[CH:3]=[C:4]([C:9]2[CH:14]=[CH:13][C:12]([C:15]#[N:16])=[CH:11][CH:10]=2)[CH:5]=[CH:6][C:7]=1[OH:8].Br[CH2:18][CH2:19][CH2:20][Cl:21]>>[Cl:21][CH2:20][CH2:19][CH2:18][O:8][C:7]1[CH:6]=[CH:5][C:4]([C:9]2[CH:14]=[CH:13][C:12]([C:15]#[N:16])=[CH:11][CH:10]=2)=[CH:3][C:2]=1[F:1]

참가 물질

3

반응물 2

HCID 80061-Bromo-3-chloropropaneHCID 222745023'-Fluoro-4'-hydroxy[1,1'-biphenyl]-4-carbonitrile

생성물 1

HCID 22994370HCID 22994370, 화합물수율 99%

실험 절차

The product from Example 167A and 1-bromo-3-chloropropane were processed as described in Example 164C to provide the title compound (99% yield). 1HNMR (300 MHz, CDCl3) δ2.30 (m, 2H), 3.80 (m, 2H), 4.25 (m, 2H), 7.12-7.75 (m, 7H); MS (DCI) m/z 290 (M+H)+.

출처 및 근거

ORD 기록
ord-67cd89c92ec043eaa8c192a52c6055e1
출처 데이터셋
uspto-grants-2003_09
특허 번호
US06620839B2

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