Tert-butyl 4-(2-carbamoylbenzofuran-5-yl)piperazine-1-carboxylate → 5-(Piperazin-1-yl)benzofuran-2-carboxamide

HRID 1172

반응식

HRID 1172 반응식
C(OC([N:8]1[CH2:13][CH2:12][N:11]([C:14]2[CH:15]=[CH:16][C:17]3[O:21][C:20]([C:22]([NH2:24])=[O:23])=[CH:19][C:18]=3[CH:25]=2)[CH2:10][CH2:9]1)=O)(C)(C)C>Cl>[N:11]1([C:14]2[CH:15]=[CH:16][C:17]3[O:21][C:20]([C:22]([NH2:24])=[O:23])=[CH:19][C:18]=3[CH:25]=2)[CH2:10][CH2:9][NH:8][CH2:13][CH2:12]1

참가 물질

3

반응물 1

HCID 11244883Tert-butyl 4-(2-carbamoylbenzofuran-5-yl)piperazine-1-carboxylate

생성물 1

HCID 98347195-(Piperazin-1-yl)benzofuran-2-carboxamide

시약·촉매·용매 1

HCID 313Hydrochloric Acid용매

실험 절차

1 g of 5-(4-tert-butoxycarbonyl-1-piperazinyl)-benzofuran-2-carboxamide is dissolved in 50 ml of methanolic HCl and stirred for I hour. After customary working up, 5-(1-piperazinyl)benzofuran-2-carboxamide, m.p. 252°-255°, is obtained.

출처 및 근거

ORD 기록
ord-b5c1249063ad41ecb9a886e640b8e144
출처 데이터셋
uspto-grants-1998_03
특허 번호
US05723614

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