4-Fluoroaniline → N2-[4-Cyano-3-(trifluoromethyl)phenyl]-N2-(cyclopropylmethyl)-N1-(4-fluorophenyl)glycinamide
반응식
[C:1]([C:3]1[CH:8]=[CH:7][C:6]([N:9]([CH2:14][CH:15]2[CH2:17][CH2:16]2)[CH2:10][C:11]([OH:13])=O)=[CH:5][C:4]=1[C:18]([F:21])([F:20])[F:19])#[N:2].[F:22][C:23]1[CH:29]=[CH:28][C:26]([NH2:27])=[CH:25][CH:24]=1>>[C:1]([C:3]1[CH:8]=[CH:7][C:6]([N:9]([CH2:14][CH:15]2[CH2:17][CH2:16]2)[CH2:10][C:11]([NH:27][C:26]2[CH:28]=[CH:29][C:23]([F:22])=[CH:24][CH:25]=2)=[O:13])=[CH:5][C:4]=1[C:18]([F:21])([F:20])[F:19])#[N:2]참가 물질
3
실험 절차
Synthesized as described for Example 91C using N-[4-cyano-3-(trifluoromethyl)phenyl]-N-(cyclopropylmethyl)glycine and 4-fluoroaniline: MS (APCI) m/z 392 (M+1).
후처리
- customSynthesized
출처 및 근거
- ORD 기록
- ord-8d62a19c591643fb9b3d060ed8158aae
- 출처 데이터셋
- uspto-grants-2010_11