4-Fluoroaniline → N2-[4-Cyano-3-(trifluoromethyl)phenyl]-N1-(4-fluorophenyl)-N2-(2,2,2-trifluoroethyl)glycinamide

HRID 1173510

반응식

HRID 1173510 반응식
[C:1]([C:3]1[CH:8]=[CH:7][C:6]([N:9]([CH2:14][C:15]([F:18])([F:17])[F:16])[CH2:10][C:11](O)=[O:12])=[CH:5][C:4]=1[C:19]([F:22])([F:21])[F:20])#[N:2].[F:23][C:24]1[CH:30]=[CH:29][C:27]([NH2:28])=[CH:26][CH:25]=1>>[C:1]([C:3]1[CH:8]=[CH:7][C:6]([N:9]([CH2:14][C:15]([F:16])([F:17])[F:18])[CH2:10][C:11]([NH:28][C:27]2[CH:29]=[CH:30][C:24]([F:23])=[CH:25][CH:26]=2)=[O:12])=[CH:5][C:4]=1[C:19]([F:20])([F:22])[F:21])#[N:2]

참가 물질

3

반응물 2

HCID 97314-FluoroanilineHCID 57633731N-[4-cyano-3-(trifluoromethyl)phenyl]-N-(2,2,2-trifluoroethyl)glycine

생성물 1

HCID 86623744N2-[4-Cyano-3-(trifluoromethyl)phenyl]-N1-(4-fluorophenyl)-N2-(2,2,2-trifluoroethyl)glycinamide

실험 절차

Synthesized as described for Example 91C using N-[4-cyano-3-(trifluoromethyl)phenyl]-N-(2,2,2-trifluoroethyl)glycine and 4-fluoroaniline: MS (APCI) m/z 420 (M+1).

후처리

  1. customSynthesized

출처 및 근거

ORD 기록
ord-f21ce18e7bb84a4dbe816227369a1f75
출처 데이터셋
uspto-grants-2010_11
특허 번호
US07834063B2

연결된 노트

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