Triphenylphosphine → (3-Cyanopropyl)triphenylphosphonium bromide

HRID 1173999

반응식

HRID 1173999 반응식
[C:1]1([P:7]([C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)[C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[Br:20][CH2:21][CH2:22][CH2:23][C:24]#[N:25]>C1(C)C=CC=CC=1>[Br-:20].[C:24]([CH2:23][CH2:22][CH2:21][P+:7]([C:1]1[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1)([C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1)[C:14]1[CH:15]=[CH:16][CH:17]=[CH:18][CH:19]=1)#[N:25]

참가 물질

4

반응물 2

HCID 11776TriphenylphosphineHCID 214124-Bromobutyronitrile

생성물 1

HCID 3036619(3-Cyanopropyl)triphenylphosphonium bromide수율 50.6%

시약·촉매·용매 1

HCID 1140Toluene용매

실험 절차

Triphenylphosphine (1.4789 g) was dissolved in anhydrous toluene (44.4 ml) and then added with 4-bromo-butyronitrile (manufactured by Tokyo Kasei Kogyo Co., Ltd.) (834.7 mg), followed by thermal reflux for 22 hours. After the reaction, a precipitated product was filtrated. The precipitate obtained through filtration was washed with toluene and thermally dried under reduced pressure, thereby obtaining the subject compound (1.1697 g) as a white solid.

후처리

  1. temperatureby thermal reflux for 22 hours
  2. customAfter the reaction
  3. filtrationa precipitated product was filtrated
  4. customThe precipitate obtained through filtration
  5. washwas washed with toluene
  6. customthermally dried under reduced pressure

출처 및 근거

ORD 기록
ord-5d23629626a24808898e5d0bd44810c0
출처 데이터셋
uspto-grants-2010_11
특허 번호
US07833991B2

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