Diisopropylethylamine → methyl (1S)-1-[({(1S,3S,4S)-4-{[(2S)-2-(2,4-dioxo-3-{[2-(3-pyridinyl)-1,3-thiazol-4-yl]methyl}-1-imidazolidinyl)-3-methylpentanoyl]amino}-3-hydroxy-5-phenyl-1-[4-(2-pyridinyl)benzyl]pentyl}amino)carbonyl]-2,2-dimethylpropylcarbamate

반응식

[NH2:1][C@@H:2]([CH2:33][C:34]1[CH:39]=[CH:38][CH:37]=[CH:36][CH:35]=1)[C@@H:3]([OH:32])[CH2:4][C@@H:5]([NH:19][C:20]([C@@H:22]([NH:27][C:28](=[O:31])[O:29][CH3:30])[C:23]([CH3:26])([CH3:25])[CH3:24])=[O:21])[CH2:6][C:7]1[CH:12]=[CH:11][C:10]([C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][N:14]=2)=[CH:9][CH:8]=1.[O:40]=[C:41]1[N:45]([CH2:46][C:47]2[N:48]=[C:49]([C:52]3[CH:53]=[N:54][CH:55]=[CH:56][CH:57]=3)[S:50][CH:51]=2)[C:44](=[O:58])[CH2:43][N:42]1[C@@H:59]([C@@H:63]([CH3:66])[CH2:64][CH3:65])[C:60](O)=[O:61].CCOP(ON1N=NC2C=CC=CC=2C1=O)(OCC)=O.C(N(CC)C(C)C)(C)C>C1COCC1>[O:40]=[C:41]1[N:45]([CH2:46][C:47]2[N:48]=[C:49]([C:52]3[CH:53]=[N:54][CH:55]=[CH:56][CH:57]=3)[S:50][CH:51]=2)[C:44](=[O:58])[CH2:43][N:42]1[C@@H:59]([CH:63]([CH3:66])[CH2:64][CH3:65])[C:60]([NH:1][C@@H:2]([CH2:33][C:34]1[CH:35]=[CH:36][CH:37]=[CH:38][CH:39]=1)[C@@H:3]([OH:32])[CH2:4][C@@H:5]([NH:19][C:20]([C@@H:22]([NH:27][C:28](=[O:31])[O:29][CH3:30])[C:23]([CH3:26])([CH3:25])[CH3:24])=[O:21])[CH2:6][C:7]1[CH:12]=[CH:11][C:10]([C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][N:14]=2)=[CH:9][CH:8]=1)=[O:61]