Morpholine, 4-(2-chloroethyl)-, hydrochloride (1:1) → Methyl-(2-morpholin-4-yl-ethyl)-(6-nitro-benzothiazol-2-yl)-amine

HRID 1174961

반응식

HRID 1174961 반응식
[CH3:1][NH:2][C:3]1[S:4][C:5]2[CH:11]=[C:10]([N+:12]([O-:14])=[O:13])[CH:9]=[CH:8][C:6]=2[N:7]=1.Cl.Cl[CH2:17][CH2:18][N:19]1[CH2:24][CH2:23][O:22][CH2:21][CH2:20]1>>[CH3:1][N:2]([CH2:17][CH2:18][N:19]1[CH2:24][CH2:23][O:22][CH2:21][CH2:20]1)[C:3]1[S:4][C:5]2[CH:11]=[C:10]([N+:12]([O-:14])=[O:13])[CH:9]=[CH:8][C:6]=2[N:7]=1

참가 물질

3

반응물 2

HCID 77210Morpholine, 4-(2-chloroethyl)-, hydrochloride (1:1)HCID 638568N-Methyl-6-nitrobenzo[D]thiazol-2-amine

생성물 1

HCID 57771793Methyl-(2-morpholin-4-yl-ethyl)-(6-nitro-benzothiazol-2-yl)-amine

실험 절차

The title compound is prepared according to the general procedure outlined in Example 61, Step 2, utilizing methyl-(6-nitro-benzothiazol-2-yl)-amine (1.18 g, 5.64 mmol) and N-(2-chloroethyl)-morpholine hydrochloride (2.45 g, 13.17 mmol) to yield 1.43 g (79%) of the product. mass spectrum (ion-spray): (m/z)=323.2 (M+1).

출처 및 근거

ORD 기록
ord-b1c1071765a44a038f29f75c10dc9a97
출처 데이터셋
uspto-grants-2010_11
특허 번호
US07838543B2

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