Morpholine, 4-(2-chloroethyl)-, hydrochloride (1:1) → Methyl-(2-morpholin-4-yl-ethyl)-(6-nitro-benzothiazol-2-yl)-amine
반응식
[CH3:1][NH:2][C:3]1[S:4][C:5]2[CH:11]=[C:10]([N+:12]([O-:14])=[O:13])[CH:9]=[CH:8][C:6]=2[N:7]=1.Cl.Cl[CH2:17][CH2:18][N:19]1[CH2:24][CH2:23][O:22][CH2:21][CH2:20]1>>[CH3:1][N:2]([CH2:17][CH2:18][N:19]1[CH2:24][CH2:23][O:22][CH2:21][CH2:20]1)[C:3]1[S:4][C:5]2[CH:11]=[C:10]([N+:12]([O-:14])=[O:13])[CH:9]=[CH:8][C:6]=2[N:7]=1참가 물질
3
실험 절차
The title compound is prepared according to the general procedure outlined in Example 61, Step 2, utilizing methyl-(6-nitro-benzothiazol-2-yl)-amine (1.18 g, 5.64 mmol) and N-(2-chloroethyl)-morpholine hydrochloride (2.45 g, 13.17 mmol) to yield 1.43 g (79%) of the product. mass spectrum (ion-spray): (m/z)=323.2 (M+1).
출처 및 근거
- ORD 기록
- ord-b1c1071765a44a038f29f75c10dc9a97
- 출처 데이터셋
- uspto-grants-2010_11