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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 1177473생성일: 2026년 10월 27일

1,2,3-Benzothiadiazole → 3-Methyl-4-(5-(1-phenylcyclopropyl)thiazolo[5,4-b]pyridine-2-yl)benzonitrile

https://huagongshe.com/reaction/1177473

반응식

참여 물질

역할이름HCID투입량
반응물1,2,3-BenzothiadiazoleHCID 67505—
반응물4-Bromo-3-methylbenzonitrileHCID 2737494—
반응물5-(1-Phenylcyclopropyl)thiazolo[5,4-b]pyridineHCID 59174874—
생성물3-Methyl-4-(5-(1-phenylcyclopropyl)thiazolo[5,4-b]pyridine-2-yl)benzonitrileHCID 67111682—

반응 단계

3-Methyl-4-(5-(1-phenylcyclopropyl)thiazolo[5,4-b]pyridine-2-yl)benzonitrile was synthesized from 5-(1-phenylcyclopropyl)thiazolo[5,4-b]pyridine (48.3 mg, 191 μmol) and 4-bromo-3-methylbenzonitrile (45.0 mg, 230 μmol) according to Reference T and the general procedure for azabenzothiazole 2-arylation as a light yellow solid. MS (ESI) m/z: Calculated: 367.1; Observed: 368.1 (M++1).

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US07842685B2
출처 데이터셋uspto-grants-2010_11
ORD IDord-1e3cbe31eb4f44c8a91e1022abf70cea
출처 메모uspto-grants-2010_11