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HRID1177473

反应详情

EQUATION

反应方程式

HRID 1177473 的结构方程式

REACTANTS

反应物

3
结构：c1ccc2snnc2c1
HCID67505

Benzo-1,2,3-thiadiazole

C6H4N2S

结构：Cc1cc(C#N)ccc1Br
HCID2737494

4-Bromo-3-methylbenzonitrile

C8H6BrN

结构：c1ccc(C2(c3ccc4ncsc4n3)CC2)cc1
HCID59174874

未命名化合物

PRODUCTS

生成物

1
结构：Cc1cc(C#N)ccc1-c1nc2ccc(C3(c4ccccc4)CC3)nc2s1
HCID67111682

未命名化合物

PROCEDURE

实验过程

3-Methyl-4-(5-(1-phenylcyclopropyl)thiazolo[5,4-b]pyridine-2-yl)benzonitrile was synthesized from 5-(1-phenylcyclopropyl)thiazolo[5,4-b]pyridine (48.3 mg, 191 μmol) and 4-bromo-3-methylbenzonitrile (45.0 mg, 230 μmol) according to Reference T and the general procedure for azabenzothiazole 2-arylation as a light yellow solid. MS (ESI) m/z: Calculated: 367.1; Observed: 368.1 (M++1).