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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 1179760생성일: 2026년 10월 27일

4-(5-Trifluoromethyl-pyridin-2-yloxy)-phenol → 3,4-dihydro-1H-isoquinoline-2-carboxylic acid 4-(5-trifluoromethylpyridin-2-yloxy)-phenyl ester

https://huagongshe.com/reaction/1179760

반응식

참여 물질

역할이름HCID투입량
반응물4-(5-Trifluoromethyl-pyridin-2-yloxy)-phenolHCID 155241—
반응물3-methyl-1-(1,2,3,4-tetrahydroisoquinoline-2-carbonyl)-1H-imidazol-3-ium iodideHCID 22047918—
생성물3,4-dihydro-1H-isoquinoline-2-carboxylic acid 4-(5-trifluoromethylpyridin-2-yloxy)-phenyl esterHCID 23635514—

반응 단계

The title compound was prepared from 4-(5-trifluoromethyl-pyridin-2-yloxy)-phenol and 3-(3,4-dihydro-1H-isoquinoline-2-carbonyl)-1-methyl-3H-imidazol-1-ium iodide. The crude product was recrystallized (ethanol) (53%). HPLC-MS m/z=415.2 (M+1), Rt: 5.3 min.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US07279470B2
출처 데이터셋uspto-grants-2007_10
ORD IDord-478889d52f73403380892516082929a6
출처 메모uspto-grants-2007_10