4-Morpholinecarbonyl chloride → HCID 69517789, 화합물

반응식

[OH:1][N:2]1[CH:6]=[C:5]([Br:7])[CH:4]=[N:3]1.[N:8]1([C:14](Cl)=[O:15])[CH2:13][CH2:12][O:11][CH2:10][CH2:9]1>>[Br:7][C:5]1[CH:4]=[N:3][N:2]([O:1][C:14]([N:8]2[CH2:13][CH2:12][O:11][CH2:10][CH2:9]2)=[O:15])[CH:6]=1

참가 물질

반응물 2

HCID 848104-Morpholinecarbonyl chloride

HCID 117449511-Hydroxy-4-bromopyrazole

생성물 1

HCID 69517789HCID 69517789, 화합물

실험 절차

The title compound was prepared from 1-hydroxy-4-bromopyrazole and 4-morpholine carbonyl chloride applying the general procedure 8. The crude product was purified by flash chromatography (Quad flash 12, EtOAc-heptane) (85%, crystals).

후처리

customThe crude product was purified by flash chromatography (Quad flash 12, EtOAc-heptane) (85%, crystals)

출처 및 근거

ORD 기록: ord-cf8439aea674486cbe1792b363ffad50
출처 데이터셋: uspto-grants-2007_10
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07279470B2

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