Acetic Anhydride → 7-Methoxyisochroman-1,3-dione
반응식
[O:1]([C:3]1[CH:4]=[C:5]([C:13]([OH:15])=[O:14])[C:6](=[CH:11][CH:12]=1)[CH2:7][C:8]([OH:10])=O)[CH3:2].C(OC(=O)C)(=O)C>C1(C)C=CC=CC=1>[O:1]([C:3]1[CH:4]=[C:5]2[C:13](=[O:14])[O:15][C:8](=[O:10])[CH2:7][C:6]2=[CH:11][CH:12]=1)[CH3:2]참가 물질
4
실험 절차
1.1 g (5.2 mmol) of 4-methoxylhomophthalic acid (IIb) was dissolved in 20 ml toluene, and 0.7 ml (7.9 mmol) of acetic anhydride was added. The mixture was heated to the reflux temperature and reacted for 0.5 h. Then, the reaction mixture was cooled to the room temperature and concentrated to dry in a reduced pressure to obtain 1.1 g of a pale yellow solid with the yield of 100%. m.p. 142-143° C.
후처리
- temperatureThe mixture was heated to the reflux temperature
- customreacted for 0.5 h
- concentrationconcentrated
- customto dry in a reduced pressure
출처 및 근거
- ORD 기록
- ord-0e854e3c0041495d83017d510ade7a4a
- 출처 데이터셋
- uspto-grants-2014_03
- 특허 번호
- US08664238B2
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