Sodium Hydroxide → HCID 67362326, 화합물
반응식
C[O:2][C:3]([C:5]1[CH:9]=[C:8]([O:10][CH2:11][CH:12]2[CH2:14][CH2:13]2)[N:7]([C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][C:16]=2[F:21])[N:6]=1)=[O:4].[OH-].[Na+]>CO>[CH:12]1([CH2:11][O:10][C:8]2[N:7]([C:15]3[CH:20]=[CH:19][CH:18]=[CH:17][C:16]=3[F:21])[N:6]=[C:5]([C:3]([OH:4])=[O:2])[CH:9]=2)[CH2:13][CH2:14]1참가 물질
4
실험 절차
The crude compound obtained in step 1 was dissolved in 10 ml of methanol. 1.4 ml of an aqueous 1 M solution of sodium hydroxide were added and the mixture was stirred overnight at room temperature. The solvent was removed in vacuo and the residue purified by preparative HPLC to give 102 mg (58%) of the title compound
후처리
- customThe solvent was removed in vacuo
- customthe residue purified by preparative HPLC
출처 및 근거
- ORD 기록
- ord-b9687e65b3084772ba68d088d01d04eb
- 출처 데이터셋
- uspto-grants-2014_03
- 특허 번호
- US08664257B2
반응 노트
불러오는 중…