Sodium Bisulfate → HCID 67124545, 화합물
반응식
[Br:1][C:2]1[CH:7]=[CH:6][C:5]([C@@H:8]2[CH2:13][C:12](=[O:14])[CH2:11][CH2:10][C@H:9]2[C:15]([O-:17])=[O:16])=[CH:4][CH:3]=1.C1([NH2+]C2CCCCC2)CCCCC1.OS([O-])(=O)=O.[Na+]>CCOC(C)=O>[Br:1][C:2]1[CH:3]=[CH:4][C:5]([C@@H:8]2[CH2:13][C:12](=[O:14])[CH2:11][CH2:10][C@H:9]2[C:15]([OH:17])=[O:16])=[CH:6][CH:7]=1참가 물질
4
실험 절차
A suspension of the product from step C (5 g, 10.46 mmol) in EtOAc (100 mL) was treated with 1M aq NaHSO4 (100 mL) at rt. The biphasic mixture was stirred for 12 h at rt and then separated. The organic layer was washed with water and brine, dried (Na2SO4), filtered and concentrated to afford the title compound. HPLC/MS: 297.0/299.0 (M+1); Rt=2.55 min.
후처리
- customseparated
- washThe organic layer was washed with water and brine
- dry with materialdried (Na2SO4)
- filtrationfiltered
- concentrationconcentrated
출처 및 근거
- ORD 기록
- ord-97cf593752b84c3d832f51155bbe8f58
- 출처 데이터셋
- uspto-grants-2014_03
- 특허 번호
- US08669252B2
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