Lithium Hydroxide → 6-Tert-butyl-2-[4-[5-[(5-cyclopropyl-1-methyl-pyrazol-3-yl)amino]-1-methyl-6-oxo-3-pyridyl]-3-(hydroxymethyl)-2-pyridyl]-8-fluoro-phthalazin-1-one

반응식

C([O:4][CH2:5][C:6]1[C:7]([N:30]2[N:39]=[CH:38][C:37]3[C:32](=[C:33]([F:44])[CH:34]=[C:35]([C:40]([CH3:43])([CH3:42])[CH3:41])[CH:36]=3)[C:31]2=[O:45])=[N:8][CH:9]=[CH:10][C:11]=1[C:12]1[CH:17]=[C:16]([NH:18][C:19]2[CH:23]=[C:22]([CH:24]3[CH2:26][CH2:25]3)[N:21]([CH3:27])[N:20]=2)[C:15](=[O:28])[N:14]([CH3:29])[CH:13]=1)(=O)C.[OH-].[Li+]>C(O)(C)C.C1COCC1.O>[C:40]([C:35]1[CH:36]=[C:37]2[C:32](=[C:33]([F:44])[CH:34]=1)[C:31](=[O:45])[N:30]([C:7]1[C:6]([CH2:5][OH:4])=[C:11]([C:12]3[CH:17]=[C:16]([NH:18][C:19]4[CH:23]=[C:22]([CH:24]5[CH2:26][CH2:25]5)[N:21]([CH3:27])[N:20]=4)[C:15](=[O:28])[N:14]([CH3:29])[CH:13]=3)[CH:10]=[CH:9][N:8]=1)[N:39]=[CH:38]2)([CH3:43])([CH3:41])[CH3:42]