Citric Acid → HCID 67566730, 화합물

HRID 1191970

반응식

HRID 1191970 반응식
[Na:1].[CH3:2][CH2:3][CH2:4][N:5]([C:9]([CH:11]([NH:17][C:18]([C:20]1[CH:21]=[CH:22][CH:23]=[CH:24][CH:25]=1)=[O:19])[CH2:12][CH2:13][C:14]([OH:16])=[O:15])=[O:10])[CH2:6][CH2:7][CH3:8].C(CN)O.C(O)(=O)CC(CC(O)=O)(C(O)=O)O>O>[Na:1].[CH3:2][CH2:3][CH2:4][N:5]([C:9]([CH:11]([NH:17][C:18]([C:20]1[CH:21]=[CH:22][CH:23]=[CH:24][CH:25]=1)=[O:19])[CH2:12][CH2:13][C:14]([OH:16])=[O:15])=[O:10])[CH2:6][CH2:7][CH3:8]

참가 물질

6

반응물 4

HCID 311Citric AcidHCID 700EthanolamineHCID 4922ProglumideHCID 5360545Sodium

생성물 1

HCID 67566730HCID 67566730, 화합물

시약·촉매·용매 1

HCID 962Water용매

실험 절차

In another embodiment, a composition for IV injection can be made as follows: add 4263 g of the sodium salt of proglumide to 15 L of water and 93 g of ethanolamine and stir until a clear solution is obtained. After buffering with citric acid, the solution is diluted to a volume of 30 L, then filtered under pressure in an inert gas into 40,000 glass vials which are sterilized under heat, yielding 40,000 vials each containing 106.6 mg sodium proglumide, equivalent to 100 mg proglumide.

후처리

  1. customis obtained
  2. additionthe solution is diluted to a volume of 30 L
  3. filtrationfiltered under pressure in an inert gas into 40,000 glass vials which
  4. temperatureunder heat

출처 및 근거

ORD 기록
ord-ee737652bf5048daa246a908955b71cd
출처 데이터셋
uspto-grants-2014_03
특허 번호
US08680145B1

연결된 노트

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