6-Ethylchrysene → 12-Ethyl-6-chrysenecarbaldehyde

HRID 1193731

반응식

HRID 1193731 반응식
[CH2:1]([C:3]1[CH:4]=[C:5]2[C:14](=[C:15]3[C:20]=1[CH:19]=[CH:18][CH:17]=[CH:16]3)[CH:13]=[CH:12][C:11]1[CH:10]=[CH:9][CH:8]=[CH:7][C:6]2=1)[CH3:2].C1C2C=CC3C(=CC([CH:39]=[O:40])=C4C=3C=CC=C4)C=2C=CC=1>C(Cl)Cl>[CH2:1]([C:3]1[C:20]2[CH:19]=[CH:18][CH:17]=[CH:16][C:15]=2[C:14]2[C:5](=[C:6]3[C:11](=[C:12]([CH:39]=[O:40])[CH:13]=2)[CH:10]=[CH:9][CH:8]=[CH:7]3)[CH:4]=1)[CH3:2]

참가 물질

4

반응물 2

HCID 759516-EthylchryseneHCID 124387746-Chrysenecarbaldehyde

생성물 1

HCID 1337539012-Ethyl-6-chrysenecarbaldehyde수율 76%

시약·촉매·용매 1

HCID 6344Dichloromethane용매

실험 절차

6-Ethylchrysene (Cambridge Chemical, Inc., 60 g, 0.234 mol) was formylated according to the procedure outlined in 1A, except that CH2Cl2 (1 L) was used as the reaction solvent. The crude material was chromatographed on a plug of SiO2 (1 kg) using PhCH3 as the eluting solvent, afforded 50.38 g (76%) of 12-ethyl-6-chrysenecarbaldehyde mp 138°-139°, (C, H).

후처리

  1. customThe crude material was chromatographed on a plug of SiO2 (1 kg)

출처 및 근거

ORD 기록
ord-9ec06c3fc0c14f46bcea6fa7f914ba6a
출처 데이터셋
uspto-grants-1989_03
특허 번호
US04810727

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