Dimethyl Sulfoxide → HCID 86745743, 화합물

HRID 1195243노트

반응식

HRID 1195243 반응식
Cl.[CH:2]1([C:5]([C:7]2([CH3:10])[CH2:9][CH2:8]2)=[NH:6])[CH2:4]C1.[Cl:11]([O-:15])(=[O:14])(=[O:13])=[O:12].[NH4+].[CH3:17]S(C)=O>>[Cl:11]([O-:15])(=[O:14])(=[O:13])=[O:12].[NH3+:6][CH:5]1[C:7]2[CH2:9][CH2:8][CH2:17][C:10]=2[CH2:4][CH2:2]1

참가 물질

4

반응물 3

HCID 679Dimethyl SulfoxideHCID 24639Ammonium perchlorateHCID 19819014HCID 19819014, 화합물

생성물 1

HCID 86745743HCID 86745743, 화합물수율 43%

반응 조건

온도
100 °C

실험 절차

To a solution of 1-cyclopropyl-1-(1-methylcyclopropyl)methanimine hydrochloride (0.060 g, 0.38 mmol) in 0.60 ml of dimethyl sulfoxide was added 0.088 g (0.75 mmol) of ammonium perchlorate. The mixture was heated with stirring at 100° C. for 20 hours. The solvent was distilled out in vacuo and ether was added to the residue. Precipitated crystals was obtained and recrystallized from ethanol to afford 0.36 g (Yield: 43%) of the desired compound.

후처리

  1. temperatureThe mixture was heated
  2. distillationThe solvent was distilled out in vacuo and ether
  3. additionwas added to the residue
  4. customPrecipitated crystals
  5. customwas obtained
  6. customrecrystallized from ethanol

출처 및 근거

ORD 기록
ord-faae784c562345d58e00a7c07ea2c7c1
출처 데이터셋
uspto-grants-1992_05
특허 번호
US05110945

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