Sodium hydride → HCID 14857350, 화합물

HRID 1195810노트

반응식

HRID 1195810 반응식
[H-].[Na+].[CH3:3][C:4]1([CH3:31])[CH:13](O)[CH:12]([C:15]2[C:16](=[O:28])[N:17]([CH2:21][C:22]3[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=3)[CH:18]=[CH:19][CH:20]=2)[C:11]2[C:6](=[CH:7][CH:8]=[C:9]([C:29]#[N:30])[CH:10]=2)[O:5]1>O1CCOCC1.N#N>[CH3:3][C:4]1([CH3:31])[CH:13]=[C:12]([C:15]2[C:16](=[O:28])[N:17]([CH2:21][C:22]3[CH:23]=[CH:24][CH:25]=[CH:26][CH:27]=3)[CH:18]=[CH:19][CH:20]=2)[C:11]2[C:6](=[CH:7][CH:8]=[C:9]([C:29]#[N:30])[CH:10]=2)[O:5]1

참가 물질

5

반응물 2

HCID 24758Sodium hydrideHCID 14857308HCID 14857308, 화합물

생성물 1

HCID 14857350HCID 14857350, 화합물

시약·촉매·용매 2

HCID 947Nitrogen용매HCID 312751,4-Dioxane용매

실험 절차

0.4 g of NaH is added to a solution of 1 g of 2,2-dimethyl-4-(1-benzyl-1,2-dihydro-2-oxo-3-pyridyl)-6-cyano-3-chromanol in 40 ml of dioxane while stirring and passing in N2, the mixture is subsequently boiled for 10 hours and evaporated, and the residue is worked up in the customary manner. 2,2-Dimethyl-4-(1-benzyl-1,2-dihydro-2-oxo-3-pyridyl)-6-cyano-3-chromene is obtained, m.p. 130°-132°.

후처리

  1. customevaporated

출처 및 근거

ORD 기록
ord-e826da9db56f4843a5352dba93c11cdb
출처 데이터셋
uspto-grants-1992_05
특허 번호
US05112839

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