Triethyl phosphite → Diethyl 2-formylbenzylphosphonate

반응식

Cl[CH2:2][C:3]1[CH:10]=[CH:9][CH:8]=[CH:7][C:4]=1[CH:5]=[O:6].[P:11]([O:18]CC)([O:15][CH2:16][CH3:17])[O:12][CH2:13][CH3:14]>>[CH:5]([C:4]1[CH:7]=[CH:8][CH:9]=[CH:10][C:3]=1[CH2:2][P:11](=[O:18])([O:15][CH2:16][CH3:17])[O:12][CH2:13][CH3:14])=[O:6]

참가 물질

반응물 2

HCID 31215Triethyl phosphite

HCID 138261832-(Chloromethyl)benzaldehyde

생성물 1

HCID 19104780Diethyl 2-formylbenzylphosphonate

실험 절차

47.9 g (0.31 mol) of 2-chloromethylbenzaldehyde were heated to 160° C. together with 51.5 g (0.31 mol) of triethyl phosphite. Ethyl chloride distilled off during the course of this. The product was purified by fractional distillation.

후처리

distillationEthyl chloride distilled off during the course of this
distillationThe product was purified by fractional distillation

출처 및 근거

ORD 기록: ord-cc0f8c24a4c24503889bed2effd1d700
출처 데이터셋: uspto-grants-1994_01
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US05278152

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