Ethyl Acetate → HCID 14988431, 화합물
반응식
[C:1]1(=[O:14])[C:11]2=[C:12]3[C:7](=[CH:8][CH:9]=[CH:10]2)[CH2:6][CH2:5][CH2:4][N:3]3[C:2]1=[O:13].[Br:15]N1C(=O)CCC1=O.C(OCC)(=O)C>CN(C=O)C>[Br:15][C:9]1[CH:8]=[C:7]2[C:12]3=[C:11]([C:1](=[O:14])[C:2](=[O:13])[N:3]3[CH2:4][CH2:5][CH2:6]2)[CH:10]=1참가 물질
5
실험 절차
A mixture of 5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinoline-1,2-dione (10 g) and N-bromosuccinimide (10 g) in DMF (60 ml) was stirred at 7020 C. for 5 hours. After cooling, to the mixture was added ethyl acetate (500 ml) and washed with water and saturated aqueous sodium chloride solution successively, and then dried over anhydrous sodium sulfate. Evaporation of ethyl acetate afforded the title compound. The compound was recrystallized from ethanol to give 14 g (98.4%) as dark red needles.
후처리
- temperatureAfter cooling, to the mixture
- washwashed with water and saturated aqueous sodium chloride solution successively
- dry with materialdried over anhydrous sodium sulfate
- customEvaporation of ethyl acetate
출처 및 근거
- ORD 기록
- ord-6d3b7d39f6ed4ef99500f80b90776203
- 출처 데이터셋
- uspto-grants-1994_01
- 특허 번호
- US05281600
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