Benzoyl Peroxide → HCID 19866635, 화합물

HRID 1199444노트

반응식

HRID 1199444 반응식
[CH3:1][O:2][C:3]1[C:12]2[C:7](=[C:8]([CH3:13])[CH:9]=[CH:10][CH:11]=2)[N:6]=[CH:5][CH:4]=1.[Br:14]N1C(=O)CCC1=O.C(OOC(=O)C1C=CC=CC=1)(=O)C1C=CC=CC=1>C(Cl)(Cl)(Cl)Cl>[Br:14][CH2:13][C:8]1[CH:9]=[CH:10][CH:11]=[C:12]2[C:7]=1[N:6]=[CH:5][CH:4]=[C:3]2[O:2][CH3:1]

참가 물질

5

반응물 3

HCID 7187Benzoyl PeroxideHCID 67184N-bromobutanimideHCID 198667274-Methoxy-8-methylquinoline

생성물 1

HCID 19866635HCID 19866635, 화합물

시약·촉매·용매 1

HCID 5943Carbon Tetrachloride용매

실험 절차

4-Methoxy-8-methylquinoline (346 mg, 2 mmole), N-bromosuccinimide (365 mg, 2.05 mmole) and benzoyl peroxide (10 mg) in CCl4 (8 ml) were heated under reflux for 2.5 hours. The mixture was cooled and the succinimide was filtered off. The filtrate was washed with dilute aqueous NaHCO3 (1×) and water (1×), dried (Na2SO4) and evaporated to yield the sub-title compound as a pale yellow solid which was recrystallised from petroleum ether/cyclohexane to give colourless needles.

후처리

  1. temperatureunder reflux for 2.5 hours
  2. temperatureThe mixture was cooled
  3. filtrationthe succinimide was filtered off
  4. washThe filtrate was washed with dilute aqueous NaHCO3 (1×) and water (1×)
  5. dry with materialdried (Na2SO4)
  6. customevaporated

출처 및 근거

ORD 기록
ord-3156530f816343e38fedfaf84bcedc38
출처 데이터셋
uspto-grants-1990_02
특허 번호
US04900751

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