Methyl 2-bromo-4-fluoro-5-nitrophenoxyformate → HCID 14370869, 화합물
반응식
[F:1][C:2]1[CH:7]=[C:6]([Br:8])[C:5]([O:9][C:10]([O:12][CH3:13])=[O:11])=[CH:4][C:3]=1[N+:14]([O-])=O.[H][H]>C(O)C.[Pt](=O)=O>[F:1][C:2]1[CH:7]=[C:6]([Br:8])[C:5]([O:9][C:10]([O:12][CH3:13])=[O:11])=[CH:4][C:3]=1[NH2:14]참가 물질
5
실험 절차
Platinum dioxide (1.0 g) was added to a solution of 2-fluoro-4-bromo-5-methoxycarbonyloxinitrobenzene (30.4 g, 0.1 mol) in ethanol (300 ml) and the solution was stirred in normal atmospheric pressure of hydrogen until absorption of hydrogen was terminated. After completion of the reaction, the catalyst was removed by filtration and the solvent was removed by distillation from the filtrate to give a brown solid (28.0 g) of 2-fluoro-4-bromo-5-methoxycarbonyloxianiline.
후처리
- customwas terminated
- customAfter completion of the reaction
- customthe catalyst was removed by filtration
- customthe solvent was removed by distillation from the filtrate
출처 및 근거
- ORD 기록
- ord-ea23dae610154e6cb766618876b7bfaf
- 출처 데이터셋
- uspto-grants-1990_02
- 특허 번호
- US04902337
반응 노트
불러오는 중…