Hydrochloric Acid → Methyl 5-chloro-3-hydroxythiophene-2-carboxylate
반응식
Cl[C:2]1([C:8]([O:10][CH3:11])=[O:9])[C:6](=[O:7])[CH:5]=[CH:4][S:3]1.[ClH:12]>C(O)(=O)C>[Cl:12][C:4]1[S:3][C:2]([C:8]([O:10][CH3:11])=[O:9])=[C:6]([OH:7])[CH:5]=1참가 물질
4
실험 절차
A solution of 2-chloro-2-methoxycarbonylthiophene-3(2H)-one (30 mmol) in acetic acid (20 ml) was saturated with dry hydrogen chloride gas. After standing for 3 days the solvent was removed under reduced pressure and the oily residue distilled to give a yellow liquid which crystallised on addition of aqueous acetic acid (m.p. 42°-44° C.).
후처리
- customthe solvent was removed under reduced pressure
- distillationthe oily residue distilled
- customto give a yellow liquid which
- customcrystallised on addition of aqueous acetic acid (m.p. 42°-44° C.)
출처 및 근거
- ORD 기록
- ord-54ac88c49b634371b5a37340dd9d777a
- 출처 데이터셋
- uspto-grants-1990_02
- 특허 번호
- US04904686
반응 노트
불러오는 중…