Tetrahydrofuran → 2-[(1-Hydroxy-3-methylbutan-2-yl)amino]-4-[5-methyl-1-(4-methylphenyl)sulfonylpyrrolo[2,3-b]pyridin-3-yl]pyrimidine-5-carbonitrile

HRID 121014

반응식

[CH2:49]1[O:50][CH2:51][CH2:52][CH2:53]1.[CH3:1][c:2]1[cH:3][c:4]2[c:5]([n:6][cH:7]1)[n:8]([S:23](=[O:24])(=[O:25])[c:26]1[cH:27][cH:28][c:29]([CH3:30])[cH:31][cH:32]1)[cH:9][c:10]2-[c:11]1[n:12][c:13]([S:19]([CH3:20])(=[O:21])=[O:22])[n:14][cH:15][c:16]1[C:17]#[N:18].[CH:40]([N:41]([CH:42]([CH3:43])[CH3:44])[CH2:45][CH3:46])([CH3:47])[CH3:48].[NH2:33][CH:34]([CH2:35][OH:36])[CH:37]([CH3:38])[CH3:39]>>[CH3:1][c:2]1[cH:3][c:4]2[c:5]([n:6][cH:7]1)[n:8]([S:23](=[O:24])(=[O:25])[c:26]1[cH:27][cH:28][c:29]([CH3:30])[cH:31][cH:32]1)[cH:9][c:10]2-[c:11]1[n:12][c:13]([NH:33][CH:34]([CH2:35][OH:36])[CH:37]([CH3:38])[CH3:39])[n:14][cH:15][c:16]1[C:17]#[N:18]