Acetone → 1-(3,5-Difluorophenyl)-2-methylpropan-2-ol

HRID 12106

반응식

HRID 12106 반응식
[F:1][C:2]1[CH:3]=[C:4]([CH:7]=[C:8]([F:10])[CH:9]=1)[CH2:5]Br.[CH3:11][C:12]([CH3:14])=[O:13]>>[F:1][C:2]1[CH:3]=[C:4]([CH2:5][C:12]([CH3:14])([OH:13])[CH3:11])[CH:7]=[C:8]([F:10])[CH:9]=1

참가 물질

3

반응물 2

HCID 180AcetoneHCID 5188963,5-Difluorobenzyl bromide

생성물 1

HCID 220634951-(3,5-Difluorophenyl)-2-methylpropan-2-ol

실험 절차

The target compound is obtained by reacting a Grignard compound, prepared from 25.0 g (121 mmol) of 3,5-difluorobenzyl bromide, with 12.6 mL (171 mmol) of acetone. Yellow oil. Yield: 13.5 g (60%).

후처리

  1. customThe target compound is obtained

출처 및 근거

ORD 기록
ord-f7612df1b54540428f756596601daa60
출처 데이터셋
uspto-grants-2010_06
특허 번호
US07727984B2

연결된 노트

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