Tetrahydrofuran → N-(1-{[4-chloro-2-(trifluoromethyl)phenyl]methyl}-1H-pyrazol-3-yl)-2,6-difluorobenzamide

HRID 1213307노트

반응식

[Br:27][CH2:28][c:29]1[c:30]([C:36]([F:37])([F:38])[F:39])[cH:31][c:32]([Cl:35])[cH:33][cH:34]1.[CH2:40]1[O:41][CH2:42][CH2:43][CH2:44]1.[CH3:17][Si:18]([N-:19][Si:20]([CH3:21])([CH3:22])[CH3:23])([CH3:24])[CH3:25].[F:1][c:2]1[c:3]([C:4](=[O:5])[NH:6][c:7]2[n:8][nH:9][cH:10][cH:11]2)[c:12]([F:16])[cH:13][cH:14][cH:15]1.[Li+:26]>>[F:1][c:2]1[c:3]([C:4](=[O:5])[NH:6][c:7]2[n:8][n:9]([CH2:28][c:29]3[c:30]([C:36]([F:37])([F:38])[F:39])[cH:31][c:32]([Cl:35])[cH:33][cH:34]3)[cH:10][cH:11]2)[c:12]([F:16])[cH:13][cH:14][cH:15]1